Edit |   |
Antigenic Specificity | Caspase 3, Active/Cleaved |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, gerbil, mouse and rat |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the large (~14-21kD) and small (~10kD) subunits of human active/cleaved caspase-3. Nuclear immunostaining of Caspase-3 is considered to be an indication of active/cleaved caspase-3. May also recognize the pro-form of caspase-3 (~32kD). Apoptosis, or programmed cell death, is a common property of all multicellular organisms. The current dogma of apoptosis suggests that the components of the core cell-death machinery are integral to cells and widely conserved across species. Caspases, a family of cysteinyl aspartate-specific proteases, are integral components of the cell death machinery (reviewed in Siegal, 2006; and Lavrik et al, 2005). They play a central role in the initiation and execution of apoptotic cell death and in inflamm |
Immunogen | Immunogen: Recombinant corresponding to catalytically active human caspase-3 protein. |
Other Names | Caspase 3, Active/Cleaved (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1) |
Gene, Accession # | Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574 |
Catalog # | MBS6005687 |
Price | $530 |
Order / More Info | Caspase 3, Active/Cleaved Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |