AIB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAIB1
Clone[50B6]
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRecognizes human AIB1. Detects a band of ~160kDa by Western blot. AIB1 is a member of the p160/steroid receptor coactivator (SRC) family, named for its common amplification in breast cancer. Members of this family include a defined nuclear receptor box motif (LxxLL) that is critical for binding to nuclear hormone receptors, and two C-terminal activation domains that bind secondary coactivators such as the p300/CREB binding protein (CBP) and CARM-1 to confer acetyltransferase or methyltransferase downstream signals, respectively. AIB1 binds to estrogen receptor (ER), and its overexpression in hormone-responsive cancers and frequent amplification in breast and other cancers make it a focus for the treatment of cancer and the study of hormone
ImmunogenImmunogen: Recombinant human AIB1.
Other Names[Nuclear receptor coactivator 3; NCoA-3; SRC-3], [NCOA3; NCOA3; ACTR; AIB1; RAC3; SRC3; pCIP; AIB-1; CTG26; SRC-3; CAGH16; KAT13B; TNRC14; TNRC16; TRAM-1; bHLHe42; AIB1; BHLHE42; RAC3; TRAM1; NCoA-3; AIB-1; pCIP; bHLHe42; RAC-3; SRC-3; TRAM-1]
Gene, Accession #[AIB1], Gene ID: 8202, NCBI: Q9Y6Q9.1, UniProt: Q9Y6Q9
Catalog #MBS565058
Price$370
Order / More InfoAIB1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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