KCNN4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | KCNN4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: KCNN4 antibody detects endogenous levels of total KCNN4. Function: Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin (PubMed:17157250, PubMed:18796614).Subunit Structure: Heterotetramer of potassium channel proteins (Probable). Interacts with MTMR6.Post-translational Modifications: Phosphorylation at His-358 by NDKB activates the channel, and conversely it's dephosphorylation by PHPT1 inhibits the chan |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Membrane. Tissue Specificity: Widely expressed in non-excitable tissues. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Horse (91%), Sheep (100%), Rabbit (100%), Dog (100%) |
| Other Names | [DHS2; hIKCa1; hKCa4; hSK4; IK; IK1; IKCa1; Intermediate conductance calcium activated potassium channel protein 4; Intermediate conductance calcium-activated potassium channel protein 4; KCa3.1; KCa4; KCNN 4; Kcnn4; KCNN4_HUMAN; Potassium calcium activated channel subfamily N member 4; Potassium intermediate/small conductance calcium activated channel, subfamily N, member 4; Putative Gardos channel; SK4; SKCa 4; SKCa4] |
| Gene, Accession # | [KCNN4], Gene ID: 3783, NCBI: NP_002241.1, UniProt: O15554 |
| Catalog # | MBS9605587 |
| Price | $240, $280 |
| Order / More Info | KCNN4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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