Human BAG3 / BAG-3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human BAG3 / BAG-3 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 0.5 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human BAG3. This protein has a number of names including Bis, CAIR-1, and BAG-3 and belongs to a family of proteins that share the BAG domain. BAG-3 binds to HSP-70 and inhibits Hsp-mediated proteasomal degradation by virtue of its C-terminal BAG domain that interacts with the ATP binding site of Hsp-70. This protein has also been shown to interact with Bcl-2 and by it self exerts weak anti-apoptotic activity but is synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis. |
| Immunogen | Immunogen Description: Synthetic peptide C-SSMTDTPGNPAAP from the C-terminus of human BAG3 (NP_004272.2). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (85%), Monkey (85%), Marmoset (85%). |
| Other Names | [BAG3 / BAG-3 (C-Terminus) IHC-plus; BAG3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BCL2-binding athanogene 3; BIS; BAG-3; CAIR-1; Docking protein cair1; BCL2-associated athanogene 3; Docking protein CAIR-1; Human BAG3; BAG-3], [BAG-3] |
| Gene, Accession # | [BAG3], Gene ID: 9531, NCBI: NP_004272.2, UniProt: O95817 |
| Catalog # | MBS247723 |
| Price | $530 |
| Order / More Info | Human BAG3 / BAG-3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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