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Antigenic Specificity | Human Tumor Necrosis Factor-alpha |
Clone | [NYRhTNFa-E2] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | ion exchange purified |
Size | 0.5 mg, 1 mg |
Concentration | 1mg/ml in PBS (after reconstitution). |
Applications | ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Intracellular Staining |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: Tumor necrosis factor is a cytokineinvolved in systemic inflammationand is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptoticcell death, cellular proliferation, differentiation, inflammation, tumorigenesisand viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells.Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer. |
Immunogen | Immunogen: r.Human TNF-a. |
Other Names | [TNF a; Tumor Necrosis Factor-alpha, Mouse-Human; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin; DIF; TNFA; TNFSF2], [TNF; TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2] |
Gene, Accession # | [TNF-a], Gene ID: 7124, NCBI: NP_000585.2 |
Catalog # | MBS140025 |
Price | $305, $455 |
Order / More Info | Human Tumor Necrosis Factor-alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |