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Antigenic Specificity | Renin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Renin Polyclonal Antibody detects endogenous levels of Renin protein. Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in REN (renin) have been shown to cause familial hyper |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Renin at AA range: 180-260 |
Other Names | [Rabbit Renin; Renin; Angiotensinogenase] |
Gene, Accession # | [REN], Gene ID: 5972, NCBI: NP_000528.1, UniProt: P00797 |
Catalog # | MBS9706656 |
Price | $130, $220, $325 |
Order / More Info | Renin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |