Phospho-MAP3K7 (S192) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MAP3K7 (S192)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine, mouse, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsDot Blot (DB), ELISA (EIA)
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DescriptionThis MAP3K7 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S192 of human MAP3K7. MAP3K7 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.
Immunogenn/a
Other Names[Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1; MAP3K7; TAK1]
Gene, Accession #[MAP3K7], Gene ID: 6885, NCBI: NP_003179.1, UniProt: O43318
Catalog #MBS9208095
Price$165, $370
Order / More InfoPhospho-MAP3K7 (S192) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSmit, L., et al., J. Biol. Chem. 279(17):17232-17240 (2004). Ono, K., et al., Biochem. Biophys. Res. Commun. 307(2):332-337 (2003). Sakurai, H., et al., J. Biol. Chem. 278(38):36916-36923 (2003). Cheung, P.C., et al., EMBO J. 22(21):5793-5805 (2003). Edlund, S., et al., Mol. Biol. Cell 14(2):529-544 (2003).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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