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Antigenic Specificity | Human Toll-like receptor 2 |
Clone | [P1F10AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: TLR2 belongs to the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) which are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. |
Immunogen | Immunogen: Anti-human TLR2 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TLR2 amino acids 221-384 purified from E Coli. |
Other Names | [TLR2; Toll-like receptor 2, Mouse Human; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD282; TLR2; TIL4], [TLR2; TLR2; TIL4; CD282; TIL4] |
Gene, Accession # | [TLR2], Gene ID: 7097, NCBI: NP_003255.2 |
Catalog # | MBS140320 |
Price | $140, $205, $505 |
Order / More Info | Human Toll-like receptor 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |