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Antigenic Specificity | VPS16 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat; |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA, WB, IHC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Please decide the specificity by homology. Plays a role in vesicle-mediated protein trafficing to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 ef |
Immunogen | Immunogen: Vacuolar protein sorting 16 homolog (S. cerevisiae) Calculated MW: 95 kDa |
Other Names | [HVPS16, VPS16] |
Gene, Accession # | [VPS16], NCBI: JAO21922.1, UniProt: Q9H269 |
Catalog # | MBS7605661 |
Price | $290 |
Order / More Info | VPS16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |