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Antigenic Specificity | TMEM107 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TMEM107 antibody is human specific. At least two isoforms of TMEM107 are known to exist. Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and BRCA1 (1,2). TMEM107 is required for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with Gli2 and Gli3 to pattern ventral and intermediate neuronal cell types (1,3). TMEM107 is also a strong candidate gene for central areolar choroidal dystrophy (CACD) (1-3). |
Immunogen | Immunogen: TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107. Buffer: TMEM107 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TMEM107 : GRVS638; PRO1268; Transmembrane protein 107; transmembrane protein 107], [TMEM107; TMEM107; GRVS638; PRO1268] |
Gene, Accession # | [TMEM107], Gene ID: 84314, NCBI: NP_115730, UniProt: Q6UX40 |
Catalog # | MBS153723 |
Price | $375 |
Order / More Info | TMEM107 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |