DCC (C-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDCC (C-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis DCC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1048-1082 amino acids from the C-terminal region of human DCC. Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Immunogenn/a
Other Names[Netrin receptor DCC; Colorectal cancer suppressor; Immunoglobulin superfamily DCC subclass member 1; Tumor suppressor protein DCC; DCC; IGDCC1]
Gene, Accession #[DCC], Gene ID: 1630, NCBI: NP_005206.2, UniProt: P43146
Catalog #MBS9204255
Price$165, $370
Order / More InfoDCC (C-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHedrick L.,et al.Genes Dev. 8:1174-1183(1994). Nusbaum C.,et al.Nature 437:551-555(2005). Fearon E.R.,et al.Science 247:49-56(1990). Nigro J.M.,et al.Cell 64:607-613(1991). Cho K.R.,et al.Genomics 19:525-531(1994).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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