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Antigenic Specificity | DCC (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DCC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1048-1082 amino acids from the C-terminal region of human DCC. Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene. |
Immunogen | n/a |
Other Names | [Netrin receptor DCC; Colorectal cancer suppressor; Immunoglobulin superfamily DCC subclass member 1; Tumor suppressor protein DCC; DCC; IGDCC1] |
Gene, Accession # | [DCC], Gene ID: 1630, NCBI: NP_005206.2, UniProt: P43146 |
Catalog # | MBS9204255 |
Price | $165, $370 |
Order / More Info | DCC (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hedrick L.,et al.Genes Dev. 8:1174-1183(1994). Nusbaum C.,et al.Nature 437:551-555(2005). Fearon E.R.,et al.Science 247:49-56(1990). Nigro J.M.,et al.Cell 64:607-613(1991). Cho K.R.,et al.Genomics 19:525-531(1994). |