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Antigenic Specificity | CCDC88A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.7 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CCDC88A protein. This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human coiled-coil domain containing 88A |
Other Names | [APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212] |
Gene, Accession # | [CCDC88A], Gene ID: 55704, NCBI: NP_001129069.1, UniProt: Q3V6T2 |
Catalog # | MBS9403742 |
Price | $255 |
Order / More Info | CCDC88A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |