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Antigenic Specificity | KCNQ4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total KCNQ4 protein. Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.Kubisch C., Cell 96:437-446(1999).Gregory S.G., Nature 441:315-321(2006).Selyanko A.A., J. Physiol. (Lond.) 522:349-355(2000). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human KCNQ4. |
Other Names | [Potassium voltage-gated channel subfamily KQT member 4; Voltage-gated potassium channel subunit Kv7.4; Potassium channel subunit alpha KvLQT4; KQT-like 4] |
Gene, Accession # | [KCNQ4], Gene ID: 9132, NCBI: NP_004691.2, UniProt: P56696 |
Catalog # | MBS9402499 |
Price | $200, $255 |
Order / More Info | KCNQ4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |