ING4 (C-term) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ING4 (C-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: bovine, chicken, mouse) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ING4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 162-195 amino acids from the C-terminal region of human ING4. Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by |
| Immunogen | n/a |
| Other Names | [Inhibitor of growth protein 4; p29ING4; ING4] |
| Gene, Accession # | [ING4], Gene ID: 51147, NCBI: NP_001121054.1, UniProt: Q9UNL4 |
| Catalog # | MBS9211973 |
| Price | $165, $370 |
| Order / More Info | ING4 (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Shiseki M.,et al.Cancer Res. 63:2373-2378(2003). Unoki M.,et al.J. Biol. Chem. 281:34677-34686(2006). Raho G.,et al.Oncogene 26:5247-5257(2007). Mao Y.M.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases. Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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