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Antigenic Specificity | Bcl10 |
Clone | [6F7-B11-F8] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malig |
Immunogen | Immunogen: Purified recombinant fragment of human BCL-10 expressed in E Coli. |
Other Names | [CLAP; Me10; CIPER; c-E10; CARMEN], [CLAP; Me10; CIPER; c-E10; CARMEN] |
Gene, Accession # | [BCL-10], Gene ID: 8915, NCBI: NP_003912.1, UniProt: O95999 |
Catalog # | MBS475637 |
Price | $335 |
Order / More Info | Bcl10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |