Human CEACAM1, 5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CEACAM1, 5 |
| Clone | [4/3/17] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), CELISA, ELISA (EIA), Western Blot (WB), Immunohistology on cryosections |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: anti-human CEACAM1, 5 (BGP, CEA, CD66a,e). Background: CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family (1). It consists of seven CEACAM (CEACAM1, CEACAM3-CEACAM8) and 11 pregnancy- specific glycoprotein (PSG1-PSG11) members. The CEA family proteins belong to the immuno-globulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of i |
| Immunogen | Immunogen: Immunogen: extracted protein of CEACAM5 |
| Other Names | [CD66ae; BGP; CEA], [CEACAM1; CEACAM1; BGP; BGP1; BGPI; BGP; BGP1; BGP-1] |
| Gene, Accession # | Gene ID: 634, NCBI: NP_001020083.1, UniProt: P13688 |
| Catalog # | MBS468042 |
| Price | $505 |
| Order / More Info | Human CEACAM1, 5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zimmermann W (2002). Carcinoembryonic antigen. In Wiley Encyclopedia of Molecular Medicine (T.Creighton, ed.), John Wiley & Sons Inc., New York, USA, pp. 459-462.Scholzel S, Zimmermann W, Schwarzkopf G, Grunert F, Rogaczewski B and Thompson J (2000).Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normaltissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. Am J Pathol 156,595-605.Kleinerman DI, Troncoso P, Lin SH, Pisters LL, Sherwood ER, Brooks T, von Eschenbach AC andHsieh JT (1995). Consistent expression of an epithelial cell adhesion molecule (C-CAM) during humanprostate development and loss of expression in prostate cancer: implication as a tumor suppressor. CancerRes 55:1215-1220. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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