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Antigenic Specificity | HSP70 (P. Falciparum) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | P. Falciparum |
Isotype | n/a |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~ 70 kDa. Specific to P. falciparum and does not cross-react to any protein from Human erythrocytes. HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 5O% identity (1). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (2). When HSC70 (consti |
Immunogen | Immunogen: His-tagged and purified PfHSP70, C-terminus (AA 365-681) |
Other Names | [Rabbit P. falciparum HSP70 (P. falciparum); HSP70_PLAFA; Cytoplasmic antigen 74.3 kDa protein] |
Gene, Accession # | [HSP70], NCBI: P11144.2, UniProt: P11144 |
Catalog # | MBS8004349 |
Price | $510 |
Order / More Info | HSP70 (P. Falciparum) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993) J. Mol. Evol.38 (1) 1-17. 2. Rothman J. (1989) Cell 59: 591-601. 3. DeLuca-Flaherty, et al. (1990) Cell. 62: 875-887. 4. Bork P., Sander C. & Valencia A. (1992) Proc. Natl Acad. Sci. USA. 89: 7290-7294. 5. Fink A.L. (1999) Physiol. Rev. 79: 425-449. 6. Pesce E.R., et al. (2008) Int J Biochem Cell Biol. 40(12): 2914-26. 7. Pavithra S.R, Banumathy G., Joy O., Singh V., Tatu U. (2004) J Biol Chem. 279(45): 46692-9. |