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Antigenic Specificity | canine von Willebrand Factor |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | n/a |
Isotype | n/a |
Format | IgG fraction |
Size | 5 mg |
Concentration | IgG concentration is 5 mg/ml, determined by absorbance using an extinction coefficient (E1%280) of 13.4. |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is specific for canine vWF as demonstrated by immunoelectrophoresis and ELISA. von Willebrand Factor (vWF, also previously referred to as Factor VIII related antigen) is a large adhesive protein produced in endothelial cells and megakaryocytes. There are two critical functions of vWF, the first being its involvement in the process of platelet adhesion and aggregation through interaction with platelet receptor glycoprotein Ib, the second being the binding and stabilization of Factor VIII (antihemophilic factor) for secretion and transport in plasma. The vWF precursor protein is synthesized with a 95,000 dalton propeptide (also known as vWF antigen-II), believed to be involved in the intracellular multimerization of the vWF subu |
Immunogen | Immunogen: Canine vWF purified from plasma. |
Other Names | [von Willebrand Factor, canine], [VWF; VWF; F8VWF; F8VWF] |
Gene, Accession # | Gene ID: 399544, NCBI: NP_001002932.1, UniProt: Q28295 |
Catalog # | MBS512179 |
Price | $300 |
Order / More Info | canine von Willebrand Factor Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Montgomery RR, Coller BS, in Hemostasis and Thrombosis, 3rd Edition, eds. RW Colman, J Hirsh, VJ Marder and EW Salzman, pp. 134-168, J.B. Lippincott Co., Philadelphia PA, USA, 1994.2. Sadler JE; von Willebrand Factor (Minireview); JBC 266:34, pp 22777- 22780, 1991. |