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Antigenic Specificity | Human Secretory phospholipase A2 receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells. In neutrophils, binding of sPLA2-IB/PLA2G1B can activate p38 MAPK to stimulate elastase release and c |
Immunogen | Immunogen: Recombinant human Secretory phospholipase A2 receptor protein(395-530AA) |
Other Names | [PLA2R; 180 kDa secretory phospholipase A2 receptor; C-type lectin domain family 13 member C; M-type receptor; CLEC13C; PLA2R1], [PLA2R1; PLA2R1; PLA2R; PLA2-R; PLA2IR; CLEC13C; PLA2G1R; CLEC13C; PLA2-R; PLA2R; Soluble PLA2-R; Soluble PLA2R] |
Gene, Accession # | [PLA2R1], Gene ID: 22925, NCBI: NP_001007268.1, UniProt: Q13018 |
Catalog # | MBS1491691 |
Price | $160, $235 |
Order / More Info | Human Secretory phospholipase A2 receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |