CK-BB, Human Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CK-BB, Human |
| Clone | 21E10 |
| Host Species | Mouse |
| Reactive Species | reactivity: human. cross reactivity: mouse, rabbit, rat |
| Isotype | IgG2b |
| Format | biotin conjugate |
| Size | 0.05 mg |
| Concentration | n/a |
| Applications | F, Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody CK-BYK/21E10 recognizes human creatine kinase B-type, also known as CKB. Human CKB is a protein of 381 amino acids (~45 kDa), expressed in a number of tissues. CKB is most abundant in adult brain, approx. 5-fold lower in the stomach, 10-fold lower in the heart and barely detectable in liver. In brain, whereas most CKB has been shown to be cytosolic, several of the reactions requiring CKB are membrane-associated. CKB belongs to the creatine kinase (CK) isoenzymes that catalyse the synthesis of phosphocreatine (PCr) and its subsequent use in the regeneration of ATP in cell types where the consumption of ATP is rapid and/or sudden. In the brain the different CK isoforms constitute an energy shuttle |
| Immunogen | Immunogen: Synthetic 17-mer peptide corresponding to the N-terminal sequence of human creatine kinase braintype |
| Other Names | n/a |
| Gene, Accession # | [CK-BB] |
| Catalog # | MBS584236 |
| Price | $375 |
| Order / More Info | CK-BB, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Sistermans, E et al; Tissue and cell-specific distribution of creatine kinase B: A new and highly specific monoclonal antibody fior use in immunohistochemistry. Cell Tissue Res 1995, 280: 435 2. Kok, Y et al; Production of native creatine kinase B in insect cells using a baculovirus expression vector. Mol Cell Biochem 1995, 143: 59 3. Shen, W et al; Expression of creatine kinase isoenzyme genes during postnatal development of rat brain cerebellum: evidence for transcriptional regulation. Biochem J 2002, 367: 369 |
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MYBIOSOURCE INC.
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