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Antigenic Specificity | AMPK beta1(Phospho-Ser181) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of AMPK b1 only when phosphorylated at Serine 181. Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non- |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 181 |
Other Names | [AMPK b1(Phospho-Ser181); AMPK, HAMPKb] |
Gene, Accession # | [AMPK beta1], Gene ID: 5564, NCBI: NP_006244.2, UniProt: Q9Y478 |
Catalog # | MBS9414499 |
Price | $200, $255 |
Order / More Info | AMPK beta1(Phospho-Ser181) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |