sMD-2 and sMD-2/TLR4, Human Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | sMD-2 and sMD-2/TLR4, Human |
| Clone | 4H1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | FS, Immunoassay (IA), Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody 4H1 reacts with soluble MD-2 (sMD-2) and the sMD-2/Toll-like receptor 4 (TLR4, CD284) complex. TLRs belong to a family of proteins that specifically recognizes and senses microbial products. They are highly conserved throughout evolution and act as innate immune recognition receptors against many pathogens. TLR4 is a functional receptor for gram-negative bacterial lipopolysaccharides (LPS). TLR4 associates with MD-2 which is absolutely required for LPS-induced activation of TLR4. MD-2 exists as a cell surface protein in association with TLR4. It also exists as secreted forms consisting of MD-2 monomers and multimers. Circulating sMD-2 is mainly present as a doublet of ~20 and 25 kD, representing |
| Immunogen | Immunogen: Baculovirally expressed His-tagged human MD-2 |
| Other Names | n/a |
| Gene, Accession # | [sMD-2 and sMD-2/TLR4] |
| Catalog # | MBS584274 |
| Price | $585 |
| Order / More Info | sMD-2 and sMD-2/TLR4, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Viriyakosol, S et al; Characterization of monoclonal antibodies to human soluble MD-2 protein. Hybridoma 2006, 25: 349 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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