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Antigenic Specificity | ILF2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes h |
Immunogen | Immunogen: Recombinant protein of human ILF2 Immunogen Species: Human |
Other Names | [NF45; PRO3063] |
Gene, Accession # | [ILF2], Gene ID: 3608, NCBI: NP_001254738.1, UniProt: Q12905 |
Catalog # | MBS9133364 |
Price | $200, $275, $430 |
Order / More Info | ILF2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |