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Antigenic Specificity | Human PRX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | DyLight 488 conjugate |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. |
Immunogen | Immunogen: E Coli-derived human PRX recombinant protein (Position: M1-K91). |
Other Names | [Rabbit IgG Human PRX DyLight 488 Conjugated, Flow Validated; Periaxin; PRX; KIAA1620] |
Gene, Accession # | [PRX], Gene ID: 57716, NCBI: NP_066007.1, UniProt: Q9BXM0 |
Catalog # | MBS1751373 |
Price | $330 |
Order / More Info | Human PRX Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: PRX periaxin. 2. Gillespie CS, Sherman DL, Fleetwood-Walker SM, Cottrell DF, Tait S, Garry EM, Wallace VC, Ure J, Griffiths IR, Smith A, Brophy PJ (Jun 2000). Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice. Neuron. 26 (2): 523-31. |