Human Histone H3.3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Histone H3.3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman.
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionVariant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of hi
ImmunogenImmunogen: Recombinant human Histone H3.3 protein
Other Names[H3F3B; H3.3B; H3F3A; H3.3A; H3F3; PP781; Histone H3.3], [H3F3A; H3F3A; H3F3; H3.3A; H3.3A; H3F3]
Gene, Accession #[H3.3], Gene ID: 3020, NCBI: NP_002098.1, UniProt: P84243
Catalog #MBS715567
Price$160, $235
Order / More InfoHuman Histone H3.3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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