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Antigenic Specificity | Human Histone H3.3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of hi |
Immunogen | Immunogen: Recombinant human Histone H3.3 protein |
Other Names | [H3F3B; H3.3B; H3F3A; H3.3A; H3F3; PP781; Histone H3.3], [H3F3A; H3F3A; H3F3; H3.3A; H3.3A; H3F3] |
Gene, Accession # | [H3.3], Gene ID: 3020, NCBI: NP_002098.1, UniProt: P84243 |
Catalog # | MBS715567 |
Price | $160, $235 |
Order / More Info | Human Histone H3.3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |