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Antigenic Specificity | Kallikrein 8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Kallikrein-8 (KLK8) detection. Background: Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen: E Coli-derived human Kallikrein 8 recombinant protein (Position: V33-G260). Human Kallikrein 8 shares 74% and 73.1% amino acid (aa) sequence identity with mouse and rat Kallikrein 8, respectively. |
Other Names | [Brain serine protease 1; BSP1; hK8; HNP; HPN; Kallikrein-8; Kallikrein8; Kallikrein 8; KLK8; KLK-8; KLK 8; Neuropsin; NP; NRPN; Ovasin; PRO322; PRSS 19; PRSS19; TADG 14; TADG14; UNQ283; O60259; Kallikrein-8; kallikrein related peptidase 8], [KLK8; KLK8; NP; HNP; NRPN; PRSS19; TADG14; NRPN; PRSS19; TADG14; hK8; NP] |
Gene, Accession # | [KLK8], Gene ID: 11202, NCBI: NP_001268360.1, UniProt: O60259 |
Catalog # | MBS178505 |
Price | $280 |
Order / More Info | Kallikrein 8 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: KLK8 kallikrein-related peptidase 8.2. Diamandis, Eleftherios P.; Deperthes, David; Lundwall, Ake (Jun 2006). Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3, 2005. Biol Chem 387 (6): 635-824.3. Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, Stephan C, Talieri M, Yousef GM (Jun 2006). A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biol Chem 387(6): 637-41. |