COPS2 (N-term), 1-30 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | COPS2 (N-term), 1-30 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: zebrafish, mouse, rat, Xenopus) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This COPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human COPS2. Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphoryla |
| Immunogen | n/a |
| Other Names | [COP9 signalosome complex subunit 2; SGN2; Signalosome subunit 2; Alien homolog; JAB1-containing signalosome subunit 2; Thyroid receptor-interacting protein 15; TR-interacting protein 15; TRIP-15; COPS2; CSN2; TRIP15] |
| Gene, Accession # | [COPS2], Gene ID: 9318, NCBI: NP_001137359.1, UniProt: P61201 |
| Catalog # | MBS9207742 |
| Price | $165, $370 |
| Order / More Info | COPS2 (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kob, R., et al. Cell Cycle 8(13):2041-2049(2009) Leal, J.F., et al. Oncogene 27(14):1961-1970(2008) Fegers, I., et al. J. Proteome Res. 6(11):4182-4188(2007) Tenbaum, S.P., et al. Biochim. Biophys. Acta 1773(9):1447-1454(2007) Papaioannou, M., et al. Nucl Recept Signal 5, E008 (2007) : |
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MYBIOSOURCE INC.
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