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Antigenic Specificity | AGT - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, horse, human, mouse, rabbit, rat, sheep |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against AGT. It was validated on Western Blot using a cell lysate as a positive control.Target Description: AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular devel |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AGT |
Other Names | [angiotensinogen preproprotein; Angiotensinogen; angiotensinogen; angiotensinogen; Serpin A8Cleaved into the following 8 chains:Angiotensin-1; Alternative name(s):; Angiotensin 1-10; Angiotensin I; Ang IAngiotensin-2; Alternative name(s):; Angiotensin 1-8; Angiotensin II; Ang IIAngiotensin-3; Alternative name(s):; Angiotensin 2-8; Angiotensin III; Ang III; Des-Asp[1]-angiotensin IIAngiotensin-4; Alternative name(s):; Angiotensin 3-8; Angiotensin IV] |
Gene, Accession # | [AGT], Gene ID: 183, NCBI: NP_000020, UniProt: P01019 |
Catalog # | MBS3206961 |
Price | $365 |
Order / More Info | AGT - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |