PTOV1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPTOV1
Clonepolyclonal
Host Speciesn/a
Reactive Speciesrat. predicted to work with: human
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDescription: Rabbit IgG polyclonal antibody for Prostate tumor-overexpressed gene 1 protein(PTOV1) detection. Tested with WB in Human;Rat. Background: Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene. It is mapped to 19q13.33. This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PTOV1 (385-414aa NFVNGIRRVIANQQQVLQRNLEQEQQQRGM), different from the related mouse and rat sequences by one amino acid. Ig Type: Rabbit IgG
Other Names[Prostate tumor-overexpressed gene 1 protein; ACID2; Activator interaction domain containing protein 2; Gcap3; prostate tumor overexpressed 1; Prostate tumor overexpressed gene 1; PTOV 1; prostate tumor overexpressed 1], [PTOV1; PTOV1; ACID2; PTOV-1; ACID2; PTOV-1]
Gene, Accession #[PTOV1], Gene ID: 53635, NCBI: NP_001292034.1, UniProt: Q86YD1
Catalog #MBS178055
Price$280
Order / More InfoPTOV1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Entrez Gene: PTOV1 prostate tumor overexpressed gene 1. 2. Santamaria A, Castellanos E, Gomez V, Benedit P, Renau-Piqueras J, Morote J, Reventos J, Thomson TM, Paciucci R (Feb 2005). PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts. Mol Cell Biol 25 (5): 1900-11. 3. Santamaria A, Fernandez PL, Farre X, Benedit P, Reventos J, Morote J, Paciucci R, Thomson TM (Feb 2003).PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle. Am J Pathol 162 (3): 897-905.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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