Edit |   |
---|---|
Antigenic Specificity | Human MALT1 |
Clone | [50] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human MALT1 antibody, clone 50 recognizes human mucosal-associated lymphoid tissue lymphoma translocation 1 (MALT1), also known as MALT lymphoma-associated translocation and paracaspase. MALT1 is an 824 amino acid ~93kDa protein belonging to the peptidase C14B family containing a single death domain and two Ig-like CD-type domains. In normal lymphocytes, MALT1 plays an important role in antigen receptor-mediated lymphocyte activation. In T-cells, MALT1 is recruited by activated CARMA1, along with Bcl-10, to form a CARMA1-Bcl10-MALT1 (CBM) complex which is involved in the activation of NF-kappaB (Yang et al. 2013). MALT1 was initially identified as a recurrent translocation t(11;18)(q21:q21) in mucosal-associated lymphomas (Horsma |
Immunogen | n/a |
Other Names | [mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform a; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; MALT lymphoma-associated translocation; MALT1 protease; caspase-like protein; mucosa associated lymphoid tissue lymphoma translocation gene 1; paracaspase; MALT1 paracaspase; MALT lymphoma-associated translocation; Paracaspase], [MALT1; MALT1; MLT; MLT1; IMD12; MLT] |
Gene, Accession # | [MALT1], Gene ID: 10892, NCBI: NP_006776.1, UniProt: Q9UDY8 |
Catalog # | MBS219431 |
Price | $430 |
Order / More Info | Human MALT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |