Phospho-WASP (Tyr291) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-WASP (Tyr291) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mousepredicted: sheep, rabbit, dog, Xenopus |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-WASP (Tyr291) Antibody detects endogenous levels of WASP only when phosphorylated at Tyr291. Description: Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.Post Translational Modifications: Phosphorylated at Tyr-291 by FYN and HCK, inducing WAS effector activity after TCR engagement. Phosphorylation at Tyr-291 enhances WAS activity in promoting actin polymerization and filopodia formation.Subunit Structure: Interacts wi |
| Immunogen | Immunogen: A synthesized peptide derived from human WASP around the phosphorylation site of Tyr291. Tissue Specificity: Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen. |
| Other Names | [Eczema thrombocytopenia; IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP_HUMAN; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome; Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein] |
| Gene, Accession # | [WASP], Gene ID: 7454, NCBI: NP_000368.1, UniProt: P42768 |
| Catalog # | MBS9610666 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-WASP (Tyr291) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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