ILRL2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityILRL2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: ILRL2 antibody detects endogenous levels of total ILRL2. Function: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.Subunit Structure: Interacts with IL1RAP; the association is enhanced by IL36B indicative for an functional signaling complex and inhibi
ImmunogenImmunogen: A synthesized peptide derived from human ILRL2 Subcellular Location: Membrane. Tissue Specificity: Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte-derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level.
Other Names[IL 1 receptor related protein 2; IL 1Rrp2; IL 36R; IL-1Rrp2; IL-36 receptor; IL1 receptor related protein 2; IL1R rp2; IL1R-rp2; Il1rl2; IL1RRP2; IL36R; ILRL2_HUMAN; Interleukin 1 receptor like 2; Interleukin 1 receptor related protein 2; Interleukin-1 receptor-like 2; Interleukin-1 receptor-related protein 2]
Gene, Accession #[ILRL2], Gene ID: 8808, NCBI: NP_003845.2, UniProt: Q9HB29
Catalog #MBS9609304
Price$240, $280
Order / More InfoILRL2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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