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Antigenic Specificity | GCK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Germinal center kinase (GCK) is the founding member of the GCK family, a group of serine/threonine kinases homologous to the yeast Ste20 kinase. GCK is activated by TNF and associated with TRAF2 (TNF receptor-associated factor 2) and MEKK1, thereby activating the SAPK/JNK pathway (1,2). GCK does not significantly phosphorylate MEKK1, instead it enhances MEKK1 oligomerization and autophosphorylation (3). GCK binds and activates MLK3, indicating that GCK may have other effectors (3). |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [GCK; GK; GLK; HHF3; HK4; HKIV; HXKP; MODY2], [GCK; GCK; GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3; HK IV; HK4] |
Gene, Accession # | [GCK], Gene ID: 2645, NCBI: P35557.1, UniProt: P35557 |
Catalog # | MBS125319 |
Price | $200, $275, $430 |
Order / More Info | GCK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |