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Antigenic Specificity | PGP9.5/ UchL1 |
Clone | [SPM575] |
Host Species | Mouse |
Reactive Species | cow, dog, guinea pig, human, mouse, porcine, rabbit, rat, sheep, zebrafish. |
Isotype | IgG2a, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistology (IH) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease. |
Immunogen | Immunogen: Native UchL1 (PGP9.5) protein from brain Quantity and Buffer: 0.5 ml at 200ug/ml with BSA and azide |
Other Names | [Gracile Axonal Dystrophy; Neuron Cytoplasmic Protein 9.5; Park5; Parkinson Disease 5; PGP95; Protein Gene Product 9.5; Ubiquitin Carboxyl-terminal Esterase L1; Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1; Ubiquitin Thioesterase L1; Ubiquitin Thiolesterase L1], [UCHL1; UCHL1; NDGOA; PARK5; PGP95; PGP9.5; Uch-L1; HEL-117; PGP 9.5; UCH-L1; PGP9.5] |
Gene, Accession # | [UCHL1], Gene ID: 7345, NCBI: NP_004172.2, UniProt: P09936 |
Catalog # | MBS438111 |
Price | $190, $340, $340 |
Order / More Info | PGP9.5/ UchL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Day IN et. al. Biochem Society Trans 14:350-351 (1986) |