SIVA Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SIVA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SIVA antibody detects endogenous levels of total SIVA. Function: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.Subunit Structure: Binds through its N-terminal region to the C-terminus of CD27 and to PXMP2/PMP22. Binds to the C-terminus of TNFRSF18/GITR. Isoform 1 binds to BCL2L1/BCLX isoform Bcl-x(L) but not to BAX. Binds to capsid protein VP2 from coxsackievirus B3. Binding of SIVA1 to CD27 can be blocked by VP2.Post-translational Modifications: Phosphorylated by ABL2/ARG in response to oxidative stress. |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Nucleus. In the nucleus, accumulates in dot-like structures. Tissue Specificity: Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep Similarity: Pig (92%), Bovine (92%), Horse (92%), Sheep (92%) |
| Other Names | [Apoptosis regulatory protein Siva; CD27 binding (Siva) protein; CD27-binding protein; CD27BP; Siva 1; Siva 2; SIVA_HUMAN; Siva1] |
| Gene, Accession # | [SIVA], Gene ID: 10572, NCBI: NP_006418.2, UniProt: O15304 |
| Catalog # | MBS9603881 |
| Price | $240, $280 |
| Order / More Info | SIVA Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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