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Antigenic Specificity | Presenilin 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1.00-1.25 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), IMM, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Presenilin-2 isoform 1 Antibody N-epitope. Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1-50 on human Presenilin-2 protein. Expression: Isoform 1 is seen in the placenta, skeletal muscle and heart while isoform 2 is seen in the heart, brain, placenta, liver, skeletal muscle and kidney. |
Other Names | [AD 3LP; AD 4; AD 5; Alzheimer disease 4; CMD1V; E5 1; Presenilin 2 (Alzheimer disease 4); PS2; PSEN 2; STM2], [PSEN2; PSEN2; AD4; PS2; AD3L; STM2; CMD1V; AD4; PS2; PSNL2; STM2; PS-2] |
Gene, Accession # | Gene ID: 5664, NCBI: NP_036618, UniProt: P49810 |
Catalog # | MBS544432 |
Price | $390 |
Order / More Info | Presenilin 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |