Presenilin 2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPresenilin 2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, monkey, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration1.00-1.25 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), IMM, Western Blot (WB)
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DescriptionAffinity Purified Presenilin-2 isoform 1 Antibody N-epitope. Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane.
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 1-50 on human Presenilin-2 protein. Expression: Isoform 1 is seen in the placenta, skeletal muscle and heart while isoform 2 is seen in the heart, brain, placenta, liver, skeletal muscle and kidney.
Other Names[AD 3LP; AD 4; AD 5; Alzheimer disease 4; CMD1V; E5 1; Presenilin 2 (Alzheimer disease 4); PS2; PSEN 2; STM2], [PSEN2; PSEN2; AD4; PS2; AD3L; STM2; CMD1V; AD4; PS2; PSNL2; STM2; PS-2]
Gene, Accession #Gene ID: 5664, NCBI: NP_036618, UniProt: P49810
Catalog #MBS544432
Price$390
Order / More InfoPresenilin 2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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