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Antigenic Specificity | CROT (N-term), 49-79 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Flow Cytometry (FC/FACS), ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CROT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-79 amino acids from the N-terminal region of human CROT. CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described. |
Immunogen | n/a |
Other Names | [Peroxisomal carnitine O-octanoyltransferase; COT; CROT; COT] |
Gene, Accession # | [CROT], Gene ID: 54677, NCBI: NP_001137407.1, UniProt: Q9UKG9 |
Catalog # | MBS9210950 |
Price | $165, $370 |
Order / More Info | CROT (N-term), 49-79 Antibody from MYBIOSOURCE INC. |
Product Specific References | Li, Y.L., et al. FEBS J. 276(1):303-314(2009) Morillas, M., et al. J. Biol. Chem. 277(13):11473-11480(2002) van der Leij, F.R., et al. Mol. Genet. Metab. 71 (1-2), 139-153 (2000) : Ferdinandusse, S., et al. Biochem. Biophys. Res. Commun. 263(1):213-218(1999) |