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Antigenic Specificity | RCC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total RCC1 protein. Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.M Dasso, Mol. Cell. Biol., Aug 1992; 12: 3337 - 3345. Hoi Yeung Li, J. Cell Biol., Mar 2003; 160: 635. Michael E. Nemergut, Science, May 2001; 292: 1540. Ian Cushman, Mol. Biol. Cell, Jan 2004; 15: 245. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human RCC1. |
Other Names | [CHC1; Cell cycle regulatory protein; Regulator of chromosome condensation] |
Gene, Accession # | [RCC1], Gene ID: 1104, NCBI: NP_001041659.1, UniProt: P18754 |
Catalog # | MBS9403722 |
Price | $200, $255 |
Order / More Info | RCC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |