RCC1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRCC1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total RCC1 protein. Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.M Dasso, Mol. Cell. Biol., Aug 1992; 12: 3337 - 3345. Hoi Yeung Li, J. Cell Biol., Mar 2003; 160: 635. Michael E. Nemergut, Science, May 2001; 292: 1540. Ian Cushman, Mol. Biol. Cell, Jan 2004; 15: 245.
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human RCC1.
Other Names[CHC1; Cell cycle regulatory protein; Regulator of chromosome condensation]
Gene, Accession #[RCC1], Gene ID: 1104, NCBI: NP_001041659.1, UniProt: P18754
Catalog #MBS9403722
Price$200, $255
Order / More InfoRCC1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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