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Antigenic Specificity | SIRT2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Sirtuins are members of the NAD-dependent histone deacetylase family of proteins that participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2 (silent information regulator-2), functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle. SIRT2 is part of a phosphorylation cascade where it is phosphorylated late in G(2), during M, and into the period of cytokinesis. Inhibition of SIRT2 is reported to rescue alpha-synuclein toxicity and modify inclusion mo |
Immunogen | Immunogen: Recombinant protein of human SIRT2 Observed Molecular Weight: 43kDa |
Other Names | [SIRT2; SIR2; SIR2L; SIR2L2] |
Gene, Accession # | [SIRT2], NCBI: AAK51133.1 |
Catalog # | MBS2519896 |
Price | $150, $225, $360 |
Order / More Info | SIRT2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |