AIMP2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AIMP2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: AIMP2 antibody is human specific. AIMP2 antibody is predicted to not cross-react with AIMP1. AIMP2 was initially identified as a part of an aminoacyl-tRNA synthesase complex (1). It was later discovered to be a cofactor and substrate of Parkin, a Ring-type E3 ubiquitin ligase that is important for the survival of dopamine neurons in Parkinson's disease; accumulation of AIMP2 in these cells lead to catecholaminergic cell death (2). AIMP2 can also bind to TRAF2, a key player in the TNF-alpha signaling pathway, causing the ubiquitination of TRAF2 by cIAP1, leading to TNF-alpha-dependent apoptosis (3). Finally, AIMP2 has been suggested to function as a tumor suppressor (4). |
| Immunogen | Immunogen: AIMP2 antibody was raised against a 16 amino acid peptide near the center of human AIMP2. Buffer: AIMP2 antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [AIMP2; P38; JTV1; JTV-1; PRO0992; Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Multisynthase complex auxiliary component p38; aminoacyl tRNA synthetase complex-interacting multifunctional protein 2], [AIMP2; AIMP2; P38; JTV1; JTV-1; PRO0992; JTV1] |
| Gene, Accession # | [AIMP2], Gene ID: 7965, NCBI: NP_006294, UniProt: Q13155 |
| Catalog # | MBS153415 |
| Price | $375 |
| Order / More Info | AIMP2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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