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Antigenic Specificity | Mouse CCL-19 |
Clone | [10J38] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Neutr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCL19/MIP3beta, also known as ELC (EBI1Ligand Chemokine), is a beta chemokine that binds specifically to the chemokine receptor CCR7/EBI1/ BLR2. Mouse (human) CCL19 cDNA encodes a 108 (98) amino acid precursor protein with a predicted 25 (21) aa signal peptide that is cleaved to form the 83 (77) aa mature secreted protein. CCL19 is distantly related to other beta chemokines (20-30% aa sequence identity). Mouse CCL19 shares 83% aa sequence homology with human CCL19. CCL19 has been shown to be constitutively expressed in various lymphoid tissues (including thymus, lymph nodes, appendix, and spleen) in dendritic cells within the T-cell zone. The expression of CCL19 is downregulated by the antiinflammatory cytokine IL10. Recombinant CCL19 has b |
Immunogen | Prparartion: This antibody was produced from hybridoma (mouse myeloma fused with spleen cells from rat) immunized with mouse recombinant protein of CCL-19 (also known as MIP-3 Beta) Antigen: Recombinant Mouse CCL-19 |
Other Names | [Ccl19; ELC; CKb11; MIP3B; Scya19; exodus-3], [Ccl19; Ccl19; ELC; CKb11; MIP3B; Scya19; exodus-3; Elc; Scya19; EBI1 ligand chemokine; ELC] |
Gene, Accession # | [CCL-19], Gene ID: 24047, NCBI: NP_036018, UniProt: O70460 |
Catalog # | MBS690093 |
Price | $490 |
Order / More Info | Mouse CCL-19 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |