ARC Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ARC |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ARC antibody detects endogenous levels of total ARC. Description: ARC Isoform 1 may be involved in RNA splicing. Interacts with TFPT. Isoform 1 oligomerizes and binds to SFRS9/SRp30C and also interacts with NPM1. Isoform 2 binds CASP2/caspase-2 and CASP8/caspase-8 and inhibits caspase-8 activity. 2 isoforms of the human protein are produced by alternative splicing.Function: Isoform 1: May be involved in RNA splicing.Subunit Structure: Oligomerizes (via CARD doamin). Interacts (via CARD domain) with CASP2; inhibits CASP2 activity in a phosphorylation-dependent manner. Interacts with CASP8; decreases CASP8 activity in a mitochondria localization-and phosphorylation-dependent manner and this interaction is dissociated by c |
| Immunogen | Immunogen: A synthesized peptide derived from human ARC Subcellular Location: Cytoplasm and Nucleus > Nucleolus. Tissue Specificity: Highly expressed in heart and skeletal muscle. Detected at low levels in placenta, liver, kidney and pancreas. Predicted Cross Reactivity: Pig Similarity: Pig (88%) |
| Other Names | [Apoptosis repressor with CARD; ARC; Muscle enriched cytoplasmic protein; Muscle-enriched cytoplasmic protein; MYC; MYP; Nol3; NOL3_HUMAN; NOP; Nop30; Nucleolar protein 3 (apoptosis repressor with CARD domain); Nucleolar protein 3; Nucleolar protein of 30 kDa] |
| Gene, Accession # | [ARC], Gene ID: 8996, NCBI: NP_001171986.1, UniProt: O60936 |
| Catalog # | MBS9600056 |
| Price | $240, $280 |
| Order / More Info | ARC Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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