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Antigenic Specificity | Chk2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Chk2 is the mammalian homologue of yeast Cds1/Rad53. In response to DNA damage, a checkpoint kinase ATM phosphorylates and activates Chk2, which in turn phosphorylates and activates p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is mutated in breast and ovarian cancer. |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acid near the N-terminus of human Chk2 |
Other Names | [CHEK2; CHK2; CDS1; RAD53; LFS2; HuCds1; PP1425; OTTHUMP00000028871], [CHEK2; CHEK2; CDS1; CHK2; LFS2; RAD53; hCds1; HuCds1; PP1425; CDS1; CHK2; RAD53; Hucds1; hCds1] |
Gene, Accession # | [Chk2], Gene ID: 11200, NCBI: NP_001005735.1, UniProt: O96017 |
Catalog # | MBS840984 |
Price | $305 |
Order / More Info | Chk2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |