Axl Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Axl antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Axl |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Axl, Sky and Mer are three members of a receptor tyrosine kinase (RTK) family that share a conserved intracellular tyrosine kinase domain and an extracellular domain similar to those seen in cell adhesion molecules. These RTKs bind the vitamin K-dependent protein growth-arrest-specific 6 (Gas6), which is structurally related to the protein S anticoagulation factor (1). Upon binding to its receptor, Gas6 activates phosphatidylinositol 3-kinase (PI3K) and its downstream targets Akt and S6K, as well as NF-kappaB (2, 3). A large body of evidence supports a role for Gas6/Axl signaling in cell growth and survival in normal and cancer cells (4). |
| Immunogen | Immunogen: Fusion protein of human AXL |
| Other Names | [AXL; JTK11; UFO] |
| Gene, Accession # | [Axl], Gene ID: 558, NCBI: NP_001690.2, UniProt: P30530 |
| Catalog # | MBS8500869 |
| Price | $310 |
| Order / More Info | Axl Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Crosier, K.E. and Crosier, P.S. (1997) Pathology 29, 131-135. 2. Demarchi, F. et al. (2001) J. Biol. Chem. 276, 31738-31744. 3. Lee, W. P. et al. (2002) Oncogene 21, 329-336. 4. Bellosta, P. et al. (1997) Oncogene 15, 2387-2397. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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