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Antigenic Specificity | IL-31 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry-paraffin (IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-31 Antibody: Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting tha |
Immunogen | Immunogen: IL-31 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of mouse IL-31. The immunogen is located within amino acids 30 - 80 of IL-31. Buffer: IL-31 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-31; 1700013B14Rik; Interleukin-31; IL-31; interleukin 31], [Il31; Il31; 1700013B14Rik; IL-31] |
Gene, Accession # | [Il31], Gene ID: 76399, NCBI: AAS82846, UniProt: Q6EAL8 |
Catalog # | MBS151553 |
Price | $375 |
Order / More Info | IL-31 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |