IL13 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | IL13 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of total IL13 antibody. IL-13 is produced by T cells and is important in the TH2 response. IL-13 targets include B cells, eosinophils, fibroblasts, mast cells and macrophages (1-3). IL-13 binds specifically to IL-13Ra1 that complexes with IL-4Ra to form the Type II IL-4R. Jak1 and Tyk2 are activated and signal through Stat3 and Stat6 (6). IL-13Ra2 is a different gene product, lacks the intracellular domain, does not complex with IL-4Ra and does not signal (1,6,7). The extracellular domain of IL-13Ra2 is often elevated in diseased states. IL-13 plays key roles in airway hyperresponsiveness (AHR) of allergic asthma (1,4,5) and modulates resistance to parasitic organisms (1). |
| Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human IL13. |
| Other Names | [ALRH; BHR1; IL-13; MGC116786; MGC116788; MGC116789; P600] |
| Gene, Accession # | [IL13], Gene ID: 3596, NCBI: NP_002179.2, UniProt: P35225 |
| Catalog # | MBS9406807 |
| Price | $255 |
| Order / More Info | IL13 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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