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Antigenic Specificity | EGFR domain III [h-R3 (Nimotuzumab)] |
Clone | [h-R3] |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | 1 mg/ml |
Applications | Block (BL), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Binds to human EGFR domain III at a site distinct from antibody 7A7 (Ab00134) (Talavera et al. 2011). Recombinant monoclonal antibody to EGFR domain III. Manufactured using a proprietary Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody h-R3 (Nimotuzumab). This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors. |
Immunogen | Immunogen: This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors. |
Other Names | [ERBB; ERBB1; HER1; PIG61; mENA; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; epidermal growth factor], [EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; ERBB; ERBB1; HER1] |
Gene, Accession # | [EGFR], Gene ID: 1956, NCBI: NP_005219.2, UniProt: P00533 |
Catalog # | MBS488342 |
Price | $425 |
Order / More Info | EGFR domain III [h-R3 (Nimotuzumab)] Antibody from MYBIOSOURCE INC. |
Product Specific References | Fernandez et al. A new monoclonal antibody for detection of EGF-receptors in western blots and paraffin-embedded tissue sections. J Cell Biochem. 1992 Jun; 49(2):157-65. PMID:1400622 |