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Antigenic Specificity | PRMT1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of PRMT1 and does not cross-react with related proteins. UniPort Summary Function: Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 ?Arg-4? (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 trans |
Immunogen | Immunogen: Purified recombinant human PRMT1 protein fragments expressed in E Coli. Cellular Localization: Nucleus; Cytoplasm |
Other Names | [ANM1; HCP1; IR1B4; HRMT1L2], [PRMT1; PRMT1; ANM1; HCP1; IR1B4; HRMT1L2] |
Gene, Accession # | [PRMT1], Gene ID: 3276, NCBI: NP_001193971.1, UniProt: Q99873 |
Catalog # | MBS857938 |
Price | $300 |
Order / More Info | PRMT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |