cIAP Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | cIAP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | cIAP Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. The two isoforms of c-IAP (c-IAP1 and c-IAP2) are structurally related to XIAP, containing 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspases-3, -7. The c-IAPs can associate with the death receptor TNF-R2, and mediate the ubiquitinization of TRAF2 following the binding of TNF-α by its receptor. Omi, a negative regulator of c-IAP, inhibits it |
| Immunogen | Immunogen: c-IAP antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human c-IAP1 c-IAP antibody detects both c-IAP1 and c-IAP2. Buffer: cIAP Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [cIAP; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1; API1; IAP2; Baculoviral IAP repeat-containing protein 2; C-IAP1; IAP-2; baculoviral IAP repeat-containing 2], [BIRC2; BIRC2; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1; API1; IAP2; MIHB; RNF48; IAP-2; hIAP-2; hIAP2] |
| Gene, Accession # | [BIRC2], Gene ID: 329, NCBI: NP_001157, UniProt: Q13490 |
| Catalog # | MBS151377 |
| Price | $375 |
| Order / More Info | cIAP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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