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Antigenic Specificity | CNR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CNR1 antibody detects endogenous levels of total CNR1. Function: G-protein coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such as delta9-tetrahydrocannabinol (THC) (PubMed:15620723, PubMed:27768894, PubMed:27851727). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP (PubMed:1718258, PubMed:21895628, PubMed:27768894). In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Widely expressed, with highest levels in fetal and adult brain. Expression levels of isoform 2 and isoform 3 are much lower than those of isoform 1. Predicted Cross Reactivity: Bovine, Horse, Sheep, Chicken Similarity: Bovine (92%), Horse (100%), Sheep (92%), Chicken (92%) |
Other Names | [CANN6; Cannabinoid receptor 1; CB-R; CB1; CB1A; CB1K5; CB1R; Central cannabinoid receptor; CNR; CNR1; CNR1_HUMAN; OTTHUMP00000016838; OTTHUMP00000214579] |
Gene, Accession # | [CNR1], Gene ID: 1268, NCBI: NP_001153698.1, UniProt: P21554 |
Catalog # | MBS9606370 |
Price | $240, $280 |
Order / More Info | CNR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |